Mass Effect 2

Shooter / Role-playing (RPG) / Adventure · 2010 · PlayStation 3, PC (Microsoft Windows), Xbox 360

A squad-based sci-fi shooter RPG in which you build a team, earn your squadmates' loyalty, and prepare for a high-stakes final assault. Your choices decide who survives, and they carry into Mass Effect 3. It was remastered in 2021 as part of the Mass Effect Legendary Edition, which changes little from the original.

Guides and missables below stop at this point. Move it forward as you play.

Quest walkthroughs

Quests for Opening / first mission. Open a quest for step-by-step directions, choices, rewards and troubleshooting. Its full walkthrough reveals that quest’s details.

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Quick tips

  • Opening / first mission

    Pick a class you'll enjoy

    Create your character here, or import a Mass Effect 1 save. Choose a class you'll enjoy for a long run. Soldier, Infiltrator and Vanguard are the straightforward damage-dealers, while Adept, Sentinel and Engineer lean on powers.

  • Opening / first mission

    Missing in Action

    Completing the intro sequence on the Normandy unlocks the "Missing in Action" achievement.

Things you can miss

Optional quests, items or choices you can lose access to by progressing past a point. Guides often call these “missables”.

  • Difficulty-locked weapons from recruitment missionsComing up

    Can be lost after: Gathering the first recruits

    A sniper rifle can be missed on Thane's recruitment mission and an SMG on Tali's. The Geth Pulse Rifle on Tali's recruitment needs Hard or Insanity until you have it. Check a current guide for exact thresholds.

All Mass Effect 2 missables by stage (contains spoilers)

Opening this list shows every missable’s name, including ones past your spoiler line. Names only, no details.

  • Difficulty-locked weapons from recruitment missions · can be lost after Gathering the first recruits
  • Big Game Hunter (thresher maw kill) · can be lost after Loyalty and recruitment window
  • Loyalty mission fail states · can be lost after Loyalty and recruitment window
  • Jack and Miranda loyalty conflict · can be lost after Loyalty and recruitment window
  • Remaining loyalty missions, upgrades and side content · can be lost after Final preparation
  • Legion's loyalty mission · can be lost after Final preparation
  • Full Normandy crew survival · can be lost after Final preparation
  • No One Left Behind · can be lost after Finale
  • Squadmate survival for Mass Effect 3 · can be lost after Finale
  • Against All Odds · can be lost after Finale

Guides and data last refreshed Nov 13, 2026. They are generated from web research and may contain mistakes.